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Active cGAS-STING signaling has also been linked with the production of certain chemokines that recruit T cells to the tumor site such as CXCL10, as well as induction of T-cell stemness (197, 215)

J.et al (2021a)

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Abbreviations DPPOS: Diabetes Prevention Program Outcomes Study GWAS: Genome-wide association study IF: Intrinsic factor MHRA: Medicines and Healthcare products Regulatory Agency PPI: Proton pump inhibitor QC: Quality control UKB: UK Biobank References Kim J, Ahn CW, Fang S, Lee HS, Park JS (2019) Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes

Abstract The intervertebral disc (IVD) is the fibrocartilaginous joint located between each vertebral body that confers flexibility and weight bearing capabilities to the spine